Coronary Sinus Reducer Stent for the Treatment of Chronic Refractory Angina Pectoris
نویسندگان
چکیده
Background Increased coronary sinus (CS) pressure can reduce myocardial ischemia by redistribution of blood from nonischemic to ischemic territories. The Coronary Sinus Reducer is a percutaneous implantable device designed to establish CS narrowing and to elevate CS pressure. In preclinical experiments, implantation of the Reducer was safe and was associated with improved ischemic parameters. In the present study, the safety and feasibility of the Coronary Sinus Reducer was evaluated in patients with refractory angina who were not candidates for revascularization.
منابع مشابه
Coronary sinus reducer stent for the treatment of chronic refractory angina pectoris: a prospective, open-label, multicenter, safety feasibility first-in-man study.
OBJECTIVES This study sought to evaluate the safety of the Coronary Sinus Reducer (Neovasc Medical, Inc., Or Yehuda, Israel) as a potential alternate therapy for patients with refractory angina who are not candidates for conventional revascularization procedures. BACKGROUND Increased coronary sinus (CS) pressure can reduce myocardial ischemia by redistribution of blood from nonischemic to isc...
متن کامل[The coronary sinus reducer stent for the treatment of chronic refractory angina pectoris].
We were very interested to read the article dealing with therapeutic options in patients with chronic refractory angina pectoris (RAP) signed by Cohen et al. 1 The authors presented an excellent review of the therapeutic options for such ''no-option'' patients suffering from chronic RAP caused by severe symptomatic and chronic coronary artery disease. May we quote Dr. Cohen and colleagues: ''Re...
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R efractory angina pectoris is a debilitating clinical condition that has typically been used to describe a subset of patients with chest pain syndrome on maximally tolerated antianginal medical therapy, demonstrable myocardial ischemia, and no coronary revascularization options (1). A multitude of novel treatment options directed at patients with refractory angina, ranging from interventional ...
متن کاملReply to comments from Paz and Shinfeld to article entitled ‘Safety and efficacy of a device to narrow the coronary sinus for the treatment of refractory angina: a single-centre real-world experience’
OBJECTIVE The coronary sinus Reducer is a recently introduced device to treat patients with severe angina symptoms refractory to optimal medical therapy and not amenable for conventional revascularisation. We aimed to assess the safety and efficacy of the Reducer in a real-world cohort of patients with refractory angina. METHODS This is a single-centre retrospective registry. Patients with se...
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Refractory angina pectoris is defined as a chronic debilitating condition characterized by the presence of chronic anginal symptoms due to a severe obstructive and/or diffuse coronary artery disease that cannot be controlled by the combination of medical therapy and/or revascularization (percutaneous or surgical). In addition, the presence of myocardial ischemia as a cause of the symptoms must ...
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